CYCLIC AMINE DERIVATIVES AND THEIR USE AS DRUGS

• Main Authors: TEIG, STEVEN, TARBY, CHRISTINE M, IMAI, MINORU, SHIOTA, TATSUKI, TAKENOUCHI, OSAMI, FURUYA, MINORU, MUROGA, YUMICO, SUDOH, MASAKI, ENDO, NORIAKI, HADA, TAKAHIKO, MORITA, TAKUYA, KATAOKA, KEN-ICHIRO, TSUTSUMI, TAKAHARU, MOREE, WILNA, SOGAWA, RYO
• Format: Patent
• Language: Bulgarian; English
• Published: 31.01.2001
• Edition: 7
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

A compound represented by general formula, a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, and their metal applications. Since these compounds inhibit the action of chemokines such as MIP-1alpha and/or MCP-1on target cells,...