Groes and groel homologs of francisella tularensis

A polypeptide comprising at least one component of an Hsp60 obtainable from Francisella tularensis, and in particular the GroEL protein, or a fragment thereof, or a variant of any of these, which polypeptide, when administered to an animal, produces an immune response which is protective against F....

Full description

Saved in:
Bibliographic Details
Main Authors MARGARET GILLIAN HARTLEY, KERRI ANNE MACK, RICHARD WILLIAM TITBALL, ANDERS SJOSTEDT, MICHAEL GREEN
Format Patent
LanguageEnglish
Published 13.03.2002
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:A polypeptide comprising at least one component of an Hsp60 obtainable from Francisella tularensis, and in particular the GroEL protein, or a fragment thereof, or a variant of any of these, which polypeptide, when administered to an animal, produces an immune response which is protective against F. tularensis infection, for use in prophylactic or therapeutic vaccination against F. tularensis. The polypeptide may be administered directly to the host, or nucleic acid encoding the polypeptide may be administered in a form in which they might be expressed in vivo. Vaccines based upon these polypeptides suitably include an additional component and in particular an adjuvant which promotes a cellular immune response.
Bibliography:Application Number: AU19820035001