Viral therapeutics

A method for identifying a substance for affecting a viral infection is described. The method comprises: a) providing a lipid globule targeting sequence, as a first component; b) providing a lipid globule, as a second component; c) contacting the two components with a substance to be tested under co...

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Bibliographic Details
Main Authors RALPH GRAHAM HOPE, JOHN MCLAUCHLAN
Format Patent
LanguageEnglish
Published 18.11.2004
Edition7
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
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Summary:A method for identifying a substance for affecting a viral infection is described. The method comprises: a) providing a lipid globule targeting sequence, as a first component; b) providing a lipid globule, as a second component; c) contacting the two components with a substance to be tested under conditions that would permit the two components to interact in the absence of the substance; and d) determining whether the substance disrupts the interaction between the first and second components; wherein the targeting sequence comprises a hepatitis C virus (HCV) core protein or a fragment, derivative, variant or homologue thereof.
Bibliography:Application Number: AU19980094227