Novel diarylamide derivatives and use thereof as medicines

This invention relates to a diarylamide derivative represented by formula (1) or a salt thereof and a pharmaceutical composition comprising, as an active ingredient, the compound: wherein, A and B denote an aromatic ring such as a benzene ring; COY and NHCOX are adjacent to each other and these subs...

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Bibliographic Details
Main Authors HARUHISA OGITA, HARUO TAKAKU, YOSHIAKI ISOBE
Format Patent
LanguageEnglish
Published 10.05.2001
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention relates to a diarylamide derivative represented by formula (1) or a salt thereof and a pharmaceutical composition comprising, as an active ingredient, the compound: wherein, A and B denote an aromatic ring such as a benzene ring; COY and NHCOX are adjacent to each other and these substituents are linked to carbon in the aromatic ring A; X denotes alkylene, alkyleneoxy, or a single bond; Y denotes an alkyl, alkoxy, hydroxyl, or substituted or unsubstituted amino group; R denotes hydrogen, halogen, hydroxyl, alkyl or the like, provided that, when A denotes a benzene ring, R does not denote hydrogen; R denotes hydrogen, halogen, hydroxyl, alkyl or the like; R and R denote a substituted or unsubstituted imino group, an oxygen atom, or a single bond; R denotes alkyl, substituted or unsubstituted phenyl or the like; and Z denotes oxygen or sulfur.
Bibliography:Application Number: AU20000074466