Process of purification of cyclosporin

Object of the invention is a process for the chromatographic preparation of cyclosporin A from a crude product containing cyclosporin complex by using a column filled with silica gel and by the application of multistep chromatography with a column filled with normal phase silica gel and by a solvent...

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Bibliographic Details
Main Authors LAJOS DEAK, ARVAI EDIT NAGYNE, ISTVANNE MISKOLCZY, GYORGYNE MAKO, VILMOS KERI
Format Patent
LanguageEnglish
Published 16.08.2001
Edition6
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Summary:Object of the invention is a process for the chromatographic preparation of cyclosporin A from a crude product containing cyclosporin complex by using a column filled with silica gel and by the application of multistep chromatography with a column filled with normal phase silica gel and by a solvent mixture containing toluene as the major component.
Bibliography:Application Number: AU19980068482