Radicicol derivatives

Radicicol derivatives represented by the following formula (I) having tyrosine kinase inhibition activity or pharmacologically acceptable salts thereof: wherein R and R are the same or different, and each represents hydrogen, alkanoyl, alkenoyl, tert-butyldiphenylsilyl or tert-butyldimethylsilyl; R...

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Main Authors CHIKARA MURAKATA, TADAKAZU AKIYAMA, SHIRO AKINAGA, MAYUMI MIYATA, YUKIMASA SHIOTSU, NOBUYOSHI AMISHIRO, YOJI INO, SHIROH SOGA, HARUMI OGAWA
Format Patent
LanguageEnglish
Published 21.12.2000
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Radicicol derivatives represented by the following formula (I) having tyrosine kinase inhibition activity or pharmacologically acceptable salts thereof: wherein R and R are the same or different, and each represents hydrogen, alkanoyl, alkenoyl, tert-butyldiphenylsilyl or tert-butyldimethylsilyl; R represents Y-R äwherein Y represents substituted or unsubstituted alkylene; and R represents CONR R (wherein R represents hydrogen, hydroxyl, substituted or unsubstituted lower alkyl, substituted or unsubstituted higher alkyl, and the like; R represents hydroxyl, substituted lower alkyl, and the like), CO2R (wherein R represents substituted lower alkyl, substituted or unsubstituted higher alkyl, and the like), and the likeü and the like; X represents halogen or is combined together with R to represent a single bond; and R is combined together with X to represent a single bond, or represents hydrogen, alkanoyl, and the like.
Bibliography:Application Number: AU19970047239