Purine and guanine derivatives

PCT No. PCT/GB96/02451 Sec. 371 Date May 19, 1997 Sec. 102(e) Date May 19, 1997 PCT Filed Oct. 7, 1996 PCT Pub. No. WO97/12888 PCT Pub. Date Apr. 10, 1997Compounds of formula (I) (I) wherein n=1 or 2; R1 is H, NH2 or halogen; R2 is H or NH2; R3 represents the group where m=0 or 1; R4 and R5 are the...

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Bibliographic Details
Main Authors JOHN GARY MONTANA, DAVID THOMAS MANALLACK, STEVEN COLIN BEASLEY
Format Patent
LanguageEnglish
Published 28.04.1997
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PCT No. PCT/GB96/02451 Sec. 371 Date May 19, 1997 Sec. 102(e) Date May 19, 1997 PCT Filed Oct. 7, 1996 PCT Pub. No. WO97/12888 PCT Pub. Date Apr. 10, 1997Compounds of formula (I) (I) wherein n=1 or 2; R1 is H, NH2 or halogen; R2 is H or NH2; R3 represents the group where m=0 or 1; R4 and R5 are the same or different and are each H, CO2H, CO2C1-6 alkyl, NHSO2CF3, tetrazole, (CR6R7)p(Y)q(CR6R7)tZ where (CR6R7)p or (CR6R7)t may be straight or branched chain bearing the substituents R6 and R7 when p and t>1; R6 and R7 are the same or different and are each C0-6 alkyl-Z; p=1-3; q=0 or 1; t=0-4, provided that t>0 wgeb q=1; Y is NH, O, S(O)u where u=0-2; Z is H, CN, CO2H, CO2C1-6 alkyl, NHSO2CF3, tetrazole, triazole, CONH2, CON(C1-6 alkyl)2, CONH(C1-6 alkyl), SO2NH (C1-6 alkyl) or SO2N(C1-6 alkyl)2; or a salt, soluate or hydrate thereof.
Bibliography:Application Number: AU19960071406