RENIN-INHIBITORY PEPTIDES

Anti-hypertensive compounds of the formula (I) in which A represents hydrogen, C1-C8-alkyl, C7-C14-aralkyl, phenylsulphonyl, tolylsulphonyl or C1-C8-alkylsulfphonyl, or represents an aminoprotective group, B represents a direct bond, or represents sarcosyl, or represents a group of the formula D rep...

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Bibliographic Details
Main Authors ROLF HENNING, ANDREAS KNORR, JOHANNES-PETER STASCH, WOLFGANG BENDER
Format Patent
LanguageEnglish
Published 17.09.1987
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Anti-hypertensive compounds of the formula (I) in which A represents hydrogen, C1-C8-alkyl, C7-C14-aralkyl, phenylsulphonyl, tolylsulphonyl or C1-C8-alkylsulfphonyl, or represents an aminoprotective group, B represents a direct bond, or represents sarcosyl, or represents a group of the formula D represents a direct bond, or represents a group of the formula wherein X represents methylene, ethylene or sulphur, E, G, J, K, L and M independently have the same meanings as B, R1 is an optionally substituted phenyl radical, and Q is a hydroxy, alkoxy or amino group, or a physiologically acceptable salt thereof.
Bibliography:Application Number: AU19870070040