Melanin production by transformed microorganisms

The present invention is directed to a process for producing melanins, their precursors and their analogs, hereinafter referred to generically as melanins. According to the invention, melanins are produced in amounts greater than about 0.2 grams dry weight per liter of growth medium. The enhanced pr...

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Bibliographic Details
Main Authors GUY DELLA-CIOPA, THOMAS H. TURPEN, MILES R. CHEDEKEL, GENADIE G. SVERLOW, LAURENCE K. GRILL, STEPHEN J. GARGER JR
Format Patent
LanguageEnglish
Published 06.08.1998
Edition6
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention is directed to a process for producing melanins, their precursors and their analogs, hereinafter referred to generically as melanins. According to the invention, melanins are produced in amounts greater than about 0.2 grams dry weight per liter of growth medium. The enhanced production of melanin can be achieved by manipulating the constituents of the growth medium, and/or attenuating fermentation conditions, and/or by genetically engineering microorganism to produce melanins, and/or mutating the microorganisms.
Bibliography:Application Number: AU19950030106