Novel deoxy and oxygen-substituted sugar-containing 14-aminosteroid compounds

Disclosed are 14-aminosteroid compounds, including pharmaceutically acceptable acid salts and esters thereof, useful in treating individuals afflicted with congestive heart failure, which compounds have the general formula: wherein R3 is a deoxy or oxygen-substituted monosaccharide sugar residue and...

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Bibliographic Details
Main Authors GILLES YVES GENAIN, JACQUES DE ROSTOLAN, SONG LIU, JEAN-JACQUES KOENIG, DAVID EDWARD PORTLOCK, RANDY STUART MUTH
Format Patent
LanguageEnglish
Published 11.06.1998
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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Summary:Disclosed are 14-aminosteroid compounds, including pharmaceutically acceptable acid salts and esters thereof, useful in treating individuals afflicted with congestive heart failure, which compounds have the general formula: wherein R3 is a deoxy or oxygen-substituted monosaccharide sugar residue and R1, R2 and R4 are various other substituents as defined herein.
Bibliography:Application Number: AU19940078009