System and methods for performing rotor assays

An analytical system comprises a frame and movable carriage. An analytical rotor is mounted on the carriage and can be translated among a sample dispensing station, a fluid dispensing station, and a label detection zone. In order to perform assays, the analyzer system requires only the introduction...

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Bibliographic Details
Main Authors STOUGHTON L. ELLSWORTH JR, ARJUNA R. KARUNARATNE, LAWRENCE M ENSLER, ERIC K GUSTAFSON
Format Patent
LanguageEnglish
Published 19.03.1997
Edition6
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PHYSICS
TESTING
TRANSPORTING
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Summary:An analytical system comprises a frame and movable carriage. An analytical rotor is mounted on the carriage and can be translated among a sample dispensing station, a fluid dispensing station, and a label detection zone. In order to perform assays, the analyzer system requires only the introduction of the analytical rotor, sample, and a volume of diluent solution. Sample within the analyzer is contained at all times within either a sample receptacle or the rotor. The method allows for the sequential addition of sample and diluent in order to perform multiple assay steps and is particularly suitable for performing heterogeneous immunoassays. The use of fluorescent label in the system allows multiple analyte detection reactions to be performed from a single sample applied to a single rotor.
Bibliography:Application Number: AU19960069090