Naphthalene derivative

Naphthalene derivatives represented by formula ÄIÜ: (wherein A is a hydrogen atom, a hydroxy group, a C7-C11 aralkyloxy group, or an alkoxy group composed of an oxy group and a C1-C12 aliphatic or alicyclic, saturated or unsaturated hydrocarbon group where the alkyl may be substituted with a C6-C10...

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Main Authors KAZUYA TAKENOUCHI, TAKAHIRO TAKEUCHI, MASAICHI HASEGAWA, KEIJI KOMORIYA, KATSUSHI TAKAHASHI
Format Patent
LanguageEnglish
Published 19.02.1998
Edition6
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Naphthalene derivatives represented by formula ÄIÜ: (wherein A is a hydrogen atom, a hydroxy group, a C7-C11 aralkyloxy group, or an alkoxy group composed of an oxy group and a C1-C12 aliphatic or alicyclic, saturated or unsaturated hydrocarbon group where the alkyl may be substituted with a C6-C10 allyloxy group; B represents O, S, CH2, O-CH2, S-CH2, CO, or CHOR ; C represents CO, CR R CO, CH2CH2CO, or CH=CHCO; D represents a hydrogen atom, NO2, NH2, CO2R , or a group having the following formula ÄIIÜ: (wherein G represents a hydrogen atom, OH, SO2NH2, CO2R , CN, or a tetrazol-5-yl group); E represents a hydrogen atom, OH, SO2NH2, CO2R , CN, or a tetrazol-5-yl group; F represents a hydrogen atom, a C1-C4 lower alkyl group, a nitro group , or a halogen atom; and R , R , R , R , R and R are, independently each other, a hydrogen atom or a C1-C4 lower alkyl group); pharmacologically acceptable salts thereof, or pharmacologically acceptable solvates thereof, which have, for example, an inhibitory effect on the production of IgE antibodies, and will be useful for prophylaxis and/or treatment of allergic diseases.
Bibliography:Application Number: AU19950025385