New 3-(substituted tetrazolyl)-4-oxo-4H-pyrido-{1,2-a}pyrimidines, salts thereof, pharmaceutical compositions containing them and process for preparing same

PCT No. PCT/HU92/00031 Sec. 371 Date Feb. 10, 1994 Sec. 102(e) Date Feb. 10, 1994 PCT Filed Aug. 13, 1992 PCT Pub. No. WO93/04065 PCT Pub. Date Mar. 4, 1993.4-oxo-4H-pyrido[1,2-a]-pyrimidines are disclosed of the formula (I) and/or (II) wherein R is a C1-6alkyl, C3-6alkenyl, C3-6alkynyl, C3-7 cycloa...

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Main Authors ISTVAN HERMECZ, KLARA GYIRES, AGNES HORVATH, LASZLO TARDOS, LELLE VASVARI, ZOLTAN KAPUI, MARIA BALOGH, ILONA PAPP, JUDIT SIPOS, JOZSEF KNOLL
Format Patent
LanguageEnglish
Published 26.10.1995
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PCT No. PCT/HU92/00031 Sec. 371 Date Feb. 10, 1994 Sec. 102(e) Date Feb. 10, 1994 PCT Filed Aug. 13, 1992 PCT Pub. No. WO93/04065 PCT Pub. Date Mar. 4, 1993.4-oxo-4H-pyrido[1,2-a]-pyrimidines are disclosed of the formula (I) and/or (II) wherein R is a C1-6alkyl, C3-6alkenyl, C3-6alkynyl, C3-7 cycloalkyl, -(CH2)n-COOR3 wherein R3 is C1 to C4 alkyl and n is 0 or 1 or a C7-8 aralkyl group, optionally substituted by one or more halogen atom(s), or by a nitro-group, R1 is a hydrogen atom or a C1-4 alkyl group, and salts thereof, as well as a process for their preparation, and pharmaceutical compositions containing them. These compounds are therapeutically useful as gastroprotectives in the treatment and prevention of ulcer.
Bibliography:Application Number: AU19920024628