Novel methods for obtaining 6-methyl 19-nor steroids and converting them into 17alpha-substituted 19-nor pregnadienes

The invention relates to the field of organic chemistry and to steroid chemistry in particular. Its particular subject are novel 6-methyl estra 4,6-dienes of general formula (I) in which A is hydrogen or a lower oxoalkyl radical and B is hydrogen, or A is a free or esterified hydroxyl and B is a low...

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Bibliographic Details
Main Authors ALAIN PIASCO, NEJIB MOHAMED NASRAOUI, CLAUDE TCHERNATINSKY
Format Patent
LanguageEnglish
Published 11.11.1993
Edition5
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Summary:The invention relates to the field of organic chemistry and to steroid chemistry in particular. Its particular subject are novel 6-methyl estra 4,6-dienes of general formula (I) in which A is hydrogen or a lower oxoalkyl radical and B is hydrogen, or A is a free or esterified hydroxyl and B is a lower alkyl radical or a lower alcynyl radical, or A and B together form the oxygen of a cetone. The invention also relates to a method of obtaining compounds of general formula (I). These compounds are valuable synthesis agents which make it possible to obtain pharmacologically active 6-methyl 19-nor pregna 4,6-dienes.
Bibliography:Application Number: AU19900057426