A DRUG-RELEASE CONTROLLING COATING MATERIAL FOR LONG ACTING FORMULATIONS

A coating material for controlling drug release, useful for long acting formulations (e.g. for once-a-day administration), and a long acting granular composition comprising a drug (especially one conventionally difficult to prepar in long acting form) coated with the coating material. This compositi...

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Bibliographic Details
Main Authors TADAYOSHI OHMURA, HIROSHI SUGIURA, ATSUSHI KAJIYAMA, SATORU YONEYA, MUNEO FUKUI, TOSHIHARU HOSONO
Format Patent
LanguageEnglish
Published 07.05.1992
Edition5
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A coating material for controlling drug release, useful for long acting formulations (e.g. for once-a-day administration), and a long acting granular composition comprising a drug (especially one conventionally difficult to prepar in long acting form) coated with the coating material. This composition may be mixed with other granular drug formulations. The drug-release controlling coating material may comprise, in a specific ratio, specific water-insoluble and low water-permeability polymer and two materials differing from each other in the pH-dependency of their solubility (pH-dependent polymer materials).
Bibliography:Application Number: AU19900051227