A PHARMACEUTICAL COMBINATION FOR THE PROPHYLAXIS AND THERAPY OF MALARIA

The present invention relates to combinations of the antimalarials artemisinin, dihydroartemisinin, arteether, artemether, artesunate or other artemisinin derivatives with one or more of the antimalarials chloroquine, 10-O-methylfloxacrine, quinine, mefloquine, amodiaquine, pyrimethamine, sulfadoxin...

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Bibliographic Details
Main Authors BANSI LAL, DIPAK KUMAR CHATTERJEE, NOEL JOHN DE SOUZA, BINDUMADHAVAN VENUGOPALAN, RICHARD HELMUT RUPP
Format Patent
LanguageEnglish
Published 05.09.1991
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to combinations of the antimalarials artemisinin, dihydroartemisinin, arteether, artemether, artesunate or other artemisinin derivatives with one or more of the antimalarials chloroquine, 10-O-methylfloxacrine, quinine, mefloquine, amodiaquine, pyrimethamine, sulfadoxine and primaquine. Synergistic effects are achieved on treatment of mammals, including humans, with subcurative doses of the individual substances.
Bibliography:Application Number: AU19880015675