FURYL OR THIENYL SUBSTITUTED DIOXANE HEXENOIC ACID DERIVATIVES

The invention concerns novel 1,3-dioxane hexenoic aids and related carboxytic acid esters and alkanesulphonamides of the formula I in which X is oxy or thio, R' is hydrogen, halogeno, trifluoromethyl, cyano and nitro and R2 is hydrogen, together with their pharmaceutically acceptable salts. The...

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Bibliographic Details
Main Authors MICHAEL JAMES SMITHERS, GEORGE ROBERT BROWN
Format Patent
LanguageEnglish
Published 12.07.1990
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention concerns novel 1,3-dioxane hexenoic aids and related carboxytic acid esters and alkanesulphonamides of the formula I in which X is oxy or thio, R' is hydrogen, halogeno, trifluoromethyl, cyano and nitro and R2 is hydrogen, together with their pharmaceutically acceptable salts. The invention also concerns processes for the production of the novel compounds and pharmaceutical compositions containing the compounds for use in the treatment of various diseases in which thromboxane A2 (TXA2) is implicated.
Bibliography:Application Number: AU19860066132