Liquid alendronate formulations

A liquid formulation of alendronic acid, or pharmaceutically acceptable salt has enough buffer so that the pH of the formulation is 4-7.5, and 15 ml of the formulation is able to raise the pH of 50 ml of 0.1N HC1 from 1 to at least 3, and preferably 4.

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Bibliographic Details
Main Authors MANEESH J. NERURKAR, WILLIAM H. HUNKE, DRAZEN OSTOVIC
Format Patent
LanguageEnglish
Published 24.04.1998
Edition6
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A liquid formulation of alendronic acid, or pharmaceutically acceptable salt has enough buffer so that the pH of the formulation is 4-7.5, and 15 ml of the formulation is able to raise the pH of 50 ml of 0.1N HC1 from 1 to at least 3, and preferably 4.
Bibliography:Application Number: AU19970046448