9-(1,2,3,4-tetrahydronaphthalen-1-yl)-1,9-dihydropurin-6-one derivatives as pde7inhibitors

• Main Authors: HAZEL JOAN DYKE, ALAN FINDLAY HAUGHAN, FRANCES CELIA ANNE GALVIN, JOHN GARY MONTANA, CATHERINE LOUISE PICKEN, RICHARD JOHN DAVENPORT, CHRISTOPHER LOWE
• Format: Patent
• Language: English
• Published: 21.11.2000
• Edition: 7
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Compounds of formula (i) wherein X-Y-Z represents NR4-C=N or N=C-NR4; R4, which can be attached to either X or Z, is a residue derived from 5,6,7,8- or 1,2,3,4-tetrahydro-naphthalene have therapeutic utility as inhibitors of PDE7.