9-(1,2,3,4-tetrahydronaphthalen-1-yl)-1,9-dihydropurin-6-one derivatives as pde7inhibitors

Compounds of formula (i) wherein X-Y-Z represents NR4-C=N or N=C-NR4; R4, which can be attached to either X or Z, is a residue derived from 5,6,7,8- or 1,2,3,4-tetrahydro-naphthalene have therapeutic utility as inhibitors of PDE7.

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Bibliographic Details
Main Authors HAZEL JOAN DYKE, ALAN FINDLAY HAUGHAN, FRANCES CELIA ANNE GALVIN, JOHN GARY MONTANA, CATHERINE LOUISE PICKEN, RICHARD JOHN DAVENPORT, CHRISTOPHER LOWE
Format Patent
LanguageEnglish
Published 21.11.2000
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of formula (i) wherein X-Y-Z represents NR4-C=N or N=C-NR4; R4, which can be attached to either X or Z, is a residue derived from 5,6,7,8- or 1,2,3,4-tetrahydro-naphthalene have therapeutic utility as inhibitors of PDE7.
Bibliography:Application Number: AU20000045898