Inhibitors of serotonin reuptake

This invention provides compounds of Formula I: where A-B is -C=CH- or -CHCH2-; n is 0 or 1; R is H or C1-C4 alkyl; R is H, methyl, or ethyl; and Aryl is naphthyl or heteroaryl, each optionally monosubstituted with a substitutent selected from the group consisting of H, halo, hydroxy, C1-C4 alkyl, C...

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Bibliographic Details
Main Authors VINCENT PATRICK ROCCO, DANIEL JAMES KOCH
Format Patent
LanguageEnglish
Published 05.01.2000
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention provides compounds of Formula I: where A-B is -C=CH- or -CHCH2-; n is 0 or 1; R is H or C1-C4 alkyl; R is H, methyl, or ethyl; and Aryl is naphthyl or heteroaryl, each optionally monosubstituted with a substitutent selected from the group consisting of H, halo, hydroxy, C1-C4 alkyl, C1-C4 alkoxy, cyano, nitro, carboxamido, and trifluoromethyl; or pharmaceutically acceptable salts or hydrates thereof, provided that when n is 1, A-B is -CHCH2-; and a method for the inhibition of serotonin reuptake in mammals.
Bibliography:Application Number: AU19990042316