High-efficiency assay for protein mannosyl transferases

The ability of protein mannosyl transferases to catalyse the transfer of mannose from the donor sugar lipid dolichyl phosphoryl mannose to the acceptor peptide is assayed. The assay provides agents or compounds that inhibit the activity of protein mannosyl transferases.

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Bibliographic Details
Main Authors AKE P ELHAMMER, FERENC J. KEZDY
Format Patent
LanguageEnglish
Published 21.11.2002
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
TESTING
THEIR RELEVANT APPARATUS
TRANSPORTING
VINEGAR
WINE
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Summary:The ability of protein mannosyl transferases to catalyse the transfer of mannose from the donor sugar lipid dolichyl phosphoryl mannose to the acceptor peptide is assayed. The assay provides agents or compounds that inhibit the activity of protein mannosyl transferases.
Bibliography:Application Number: AU3826302