TETRAHYDROTHIOPHENE DERIVATIVES
A compound of the formula [I] and pharmaceutically acceptable salts thereof; and a synthetic intermediate represented by the fomula [II] and pharmaceutically acceptable salts thereof, wherein R 1 is hydrogen or lower alkyl; R 2 is hydrogen or a protective group of thiol; R 3 is hydroxy, a remainder...
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Main Authors | , , , , , |
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Format | Patent |
Language | English |
Published |
02.09.1993
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Subjects | |
Online Access | Get full text |
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Summary: | A compound of the formula [I] and pharmaceutically acceptable salts thereof; and a synthetic intermediate represented by the fomula [II] and pharmaceutically acceptable salts thereof, wherein R 1 is hydrogen or lower alkyl; R 2 is hydrogen or a protective group of thiol; R 3 is hydroxy, a remainder of ester group or a remainder of amido group; A is straight or branched lower alkylene, and the sulfur atom in the side chain may be directly join with -CO- to conform a thiolactone ring. The compounds of this invention have excellent thymulin-like activities and are expected to be useful for treatment of various immune disorders such as immunodeficiency and autoimmune diseases. |
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Bibliography: | Application Number: AU19930033860 |