7-¬(piperidin-1-yl)-propoxy|-chromen-4-one derivatives, their preparation and their pharmaceutical use

7-[3-[4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl]propoxy]-chromen-4-one derivatives having the formula (I):wherein R is hydrogen, CHO, CH2OR2 or COOH; R1 is hydrogen or CH2OH; and R2 is alkyl having 1 to 4 carbon atoms with the proviso that one of substituents R and R1 should be hydrogen, as we...

Full description

Saved in:
Bibliographic Details
Main Authors JOSE A ORTIZ, JORDI BOLOS, RAFAEL FOGUET, AURELIO SACRISTAN, JOSEP M CASTELLO
Format Patent
LanguageEnglish
Published 26.07.1999
Edition6
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:7-[3-[4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl]propoxy]-chromen-4-one derivatives having the formula (I):wherein R is hydrogen, CHO, CH2OR2 or COOH; R1 is hydrogen or CH2OH; and R2 is alkyl having 1 to 4 carbon atoms with the proviso that one of substituents R and R1 should be hydrogen, as well as their pharmaceutically acceptable salts. The process for their preparation and the pharmaceutical compositions containing them are also described. The compounds are new and are useful in the treatment of psychosis, schizophrenia and allergy.
Bibliography:Application Number: AU2514399