2,3-dihydroquinazolin compounds as NAV1.8 inhibitors

Abstract The present invention relates to Nav1.8 Inhibitor 2,3-dihydroquinazolin compounds of Formula (X); wherein Y', X', 1', R", R 2 , RT, R 5', R 6', R 7, and z' are as defined herein; or pharmaceutically acceptable salts or tautomer forms thereof, corresponding...

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Main Authors Jie GUANG, Mark ELBAN, Maben YING, William H. MILLER, Joseph J. ROMANO, David G. WASHBURN, Tram H. HOANG, Ming-Hsun HO, Roderick S. DAVIS, Mythily VIMAL
Format Patent
LanguageEnglish
Published 14.12.2023
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Summary:Abstract The present invention relates to Nav1.8 Inhibitor 2,3-dihydroquinazolin compounds of Formula (X); wherein Y', X', 1', R", R 2 , RT, R 5', R 6', R 7, and z' are as defined herein; or pharmaceutically acceptable salts or tautomer forms thereof, corresponding pharmaceutical compositions or formulations, methods or processes of compound preparation, methods, compounds for use in, uses for and/or combination therapies for treating pain and/or pain-related or associated disease(s), disorder(s) or conditionss, respectively. R 3R X N(x) I5 (X
Bibliography:Application Number: AU20230270195