Binding molecules that inhibit cancer growth

Abstract The invention provides means and methods for inhibiting growth of a cancer. The means in some embodiments comprise proteins and antibodies that binds an extracellular part of a membrane associated member of the epidermal growth factor (EGF) receptor family and an extracellular part of a mem...

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Main Authors Batlle, Eduard, Logtenberg, Ton, Herpers, Bram, Throsby, Mark, Clevers, Johannes Carolus, Vries, Robert Gerhardus Jacob
Format Patent
LanguageEnglish
Published 21.09.2023
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Abstract Abstract The invention provides means and methods for inhibiting growth of a cancer. The means in some embodiments comprise proteins and antibodies that binds an extracellular part of a membrane associated member of the epidermal growth factor (EGF) receptor family and an extracellular part of a membrane associated member of a WNT signaling pathway. Further provided are various cells and assays that are helpful in the production of the proteins, antibodies and cells.
AbstractList Abstract The invention provides means and methods for inhibiting growth of a cancer. The means in some embodiments comprise proteins and antibodies that binds an extracellular part of a membrane associated member of the epidermal growth factor (EGF) receptor family and an extracellular part of a membrane associated member of a WNT signaling pathway. Further provided are various cells and assays that are helpful in the production of the proteins, antibodies and cells.
Author Clevers, Johannes Carolus
Vries, Robert Gerhardus Jacob
Throsby, Mark
Logtenberg, Ton
Herpers, Bram
Batlle, Eduard
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Snippet Abstract The invention provides means and methods for inhibiting growth of a cancer. The means in some embodiments comprise proteins and antibodies that binds...
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SubjectTerms CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
Title Binding molecules that inhibit cancer growth
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