Binding molecules that inhibit cancer growth

Abstract The invention provides means and methods for inhibiting growth of a cancer. The means in some embodiments comprise proteins and antibodies that binds an extracellular part of a membrane associated member of the epidermal growth factor (EGF) receptor family and an extracellular part of a mem...

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Bibliographic Details
Main Authors Batlle, Eduard, Logtenberg, Ton, Herpers, Bram, Throsby, Mark, Clevers, Johannes Carolus, Vries, Robert Gerhardus Jacob
Format Patent
LanguageEnglish
Published 21.09.2023
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:Abstract The invention provides means and methods for inhibiting growth of a cancer. The means in some embodiments comprise proteins and antibodies that binds an extracellular part of a membrane associated member of the epidermal growth factor (EGF) receptor family and an extracellular part of a membrane associated member of a WNT signaling pathway. Further provided are various cells and assays that are helpful in the production of the proteins, antibodies and cells.
Bibliography:Application Number: AU20230222928