METHODS AND COMPOSITIONS FOR TARGETED DELIVERY OF INTRACELLULAR BIOLOGICS

Provided herein are methods and compositions for generating a pool of polypeptide variants, each with a covalently attached unique single-stranded DNA (ssDNA) barcode that allows screening and selection of the associated polypeptide variants.

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Bibliographic Details
Main Authors HONG, Vu Phong, BECONI, Maria G
Format Patent
LanguageEnglish
Published 15.08.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Provided herein are methods and compositions for generating a pool of polypeptide variants, each with a covalently attached unique single-stranded DNA (ssDNA) barcode that allows screening and selection of the associated polypeptide variants.
Bibliography:Application Number: AU20230216373