Bridged tricyclic carbamoylpyridone compounds and their pharmaceutical use

Abstract Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): W2-X2 \ L R o OH including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, Y, L, X, Z, W1, and/or W2 are as defined herein...

Full description

Saved in:
Bibliographic Details
Main Authors GUO, Hongyan, CHU, Hang, HAN, Xiaochun, PYUN, Hyung-Jung, LI, Jiayao, SCHWARZWALDER, Gregg M, SHAPIRO, Nathan D, YANG, Hong, GONZALEZ BUENROSTRO, Ana Z, SCHROEDER, Scott D, JIANG, Lan, WU, Qiaoyin, MITCHELL, Michael L, SHIVAKUMAR, Devleena M, ZHANG, Jennifer R
Format Patent
LanguageEnglish
Published 10.08.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:Abstract Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): W2-X2 \ L R o OH including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, Y, L, X, Z, W1, and/or W2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
Bibliography:Application Number: AU20230204700