Dry powder treprostinil for the treatment of pulmonary hypertension

A dry powder inhalation treatment for pulmonary arterial hypertension includes a dose of dry particles comprising greater than 25 micrograms of treprostinil enclosed in a capsule. The dry particles can include treprostinil, a wetting agent, a hy-drophobicity modifying agent, a pH modifying agent and...

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Bibliographic Details
Main Authors ROSCIGNO, Robert, MAYNOR, Benjamin, FARRER, Brian, SPRAGUE, Jacob
Format Patent
LanguageEnglish
Published 06.04.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A dry powder inhalation treatment for pulmonary arterial hypertension includes a dose of dry particles comprising greater than 25 micrograms of treprostinil enclosed in a capsule. The dry particles can include treprostinil, a wetting agent, a hy-drophobicity modifying agent, a pH modifying agent and a buffer. A method of treating a patient having pulmonary arterial hyperten-sion includes providing a patient a dry powder inhaler, providing the patient at least one capsule for use in the dry powder inhaler, the capsule including at least 25 micrograms oftreprostinil.
Bibliography:Application Number: AU20230201307