Macrocyclic immunomodulators

MACROCYCLIC IMMUNOMODULATORS Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (1) or (II) including sterioisomers and pharmaceutically acceptable salts thereof, wherein R, R1, R2a, R2b, R2c, R3, R4, R5, R6, R6a, R6b, R6c, m and n are as defined her...

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Bibliographic Details
Main Authors PUNNA, Sreenivas, MCMURTRIE, Darren J, ROTH, Howard S, SINGH, Rajinder, ZHANG, Penglie, MALATHONG, Viengkham, MCMAHON, Jeffrey
Format Patent
LanguageEnglish
Published 02.03.2023
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:MACROCYCLIC IMMUNOMODULATORS Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (1) or (II) including sterioisomers and pharmaceutically acceptable salts thereof, wherein R, R1, R2a, R2b, R2c, R3, R4, R5, R6, R6a, R6b, R6c, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
Bibliography:Application Number: AU20230200565