CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF

Provided herein are oligomeric compounds comprising a bicycle ligand and a modified oligonucleotide. This compound may comprise a bicycle ligand as the cell-targeting moiety, and may also comprise a conjugate linker to connect the bicycle ligand and modified oligonucleotide. This compound may be use...

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Bibliographic Details
Main Authors SETH, Punit, STANWAY, Steven, SKYNNER, Michael, CARRER, Michele, VAN RIETSCHOTEN, Katerine, OESTERGAARD, Michael, RIGBY, Michael, URBONAS, Liudvikas, TANOWITZ, Michael
Format Patent
LanguageEnglish
Published 07.03.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Provided herein are oligomeric compounds comprising a bicycle ligand and a modified oligonucleotide. This compound may comprise a bicycle ligand as the cell-targeting moiety, and may also comprise a conjugate linker to connect the bicycle ligand and modified oligonucleotide. This compound may be used in conjunction with a phamaceutically acceptable salt.
Bibliography:Application Number: AU20220354260