COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF ANGIOPOIETIN-LIKE 3 (ANGPTL3) PROTEIN

Compositions and methods useful to reduce expression of Angiopoietin-like 3 (ANGPTL3) gene and for treatment of ANGPTL3-associated diseases and conditions are provided. Provided are ANGPTL3 dsRNA agents, ANGPTL3 antisense polynucleotide agents, compositions comprising ANGPTL3 dsRNA agents, and, comp...

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Bibliographic Details
Main Authors SHAO, Pengcheng Patrick, SHU, Dongxu
Format Patent
LanguageEnglish
Published 21.03.2024
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:Compositions and methods useful to reduce expression of Angiopoietin-like 3 (ANGPTL3) gene and for treatment of ANGPTL3-associated diseases and conditions are provided. Provided are ANGPTL3 dsRNA agents, ANGPTL3 antisense polynucleotide agents, compositions comprising ANGPTL3 dsRNA agents, and, compositions comprising ANGPTL3 antisense polynucleotide agents that can be used to reduce ANGPTL3 expression in cells and subjects.
Bibliography:Application Number: AU20220352799