METHOD OF TREATING MULTIPLE MYELOMA

Provided herein are methods of treating multiple myeloma and methods of inhibiting amyloid formation in a subject. The methods provided herein include the administration of an antibody that binds to misfolded light chains in combination with an anti-CD38 antibody. The anti-CD38 is for example Daratu...

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Bibliographic Details
Main Authors SPECTOR, Michael, SOBOLOV-JAYNES, Susan
Format Patent
LanguageEnglish
Published 11.04.2024
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are methods of treating multiple myeloma and methods of inhibiting amyloid formation in a subject. The methods provided herein include the administration of an antibody that binds to misfolded light chains in combination with an anti-CD38 antibody. The anti-CD38 is for example Daratumumab, Isatuximab, CID- 103 (CASI Pharma), or Moro3087 (Morphosys) or a combination thereof.
Bibliography:Application Number: AU20220346750