FUSED HETEROCYCLIC RINGS AS RIPK1 INHIBITORS

The invention provides novel substituted heterocyclic rings represented by Formula I, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of RIPK1 and the therape...

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Bibliographic Details
Main Authors PARK, Kitae, KIM, Minha, SEO, Jeongbeob, HAN, Cheolkyu, CHOI, Sungmin, KIM, Jinyoung, JEON, Seeun, KWON, Youngeun, KANG, Hongjun, JEONG, Heejin, YOON, Cheolhwan, KIM, Sunjoo, KIM, Namhee, HAN, Sangbae, MIN, Jiae, YANG, Inho
Format Patent
LanguageEnglish
Published 28.03.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides novel substituted heterocyclic rings represented by Formula I, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of RIPK1 and the therapeutic methods.
Bibliography:Application Number: AU20220346718