HETEROCYCLIC COMPOUNDS AND METHODS OF USE
The present disclosure provides compounds useful for the inhibition of KRAS G12D. The compounds have a general Formula I: wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions...
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Main Authors | , , , , , , , , , |
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Format | Patent |
Language | English |
Published |
15.02.2024
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Subjects | |
Online Access | Get full text |
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Abstract | The present disclosure provides compounds useful for the inhibition of KRAS G12D. The compounds have a general Formula I: wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer. |
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AbstractList | The present disclosure provides compounds useful for the inhibition of KRAS G12D. The compounds have a general Formula I: wherein the variables of Formula I are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer. |
Author | STELLWAGEN, John LANMAN, Brian Alan RAHIMOFF, Rene ZHAO, Wei WURZ, Ryan Paul PETTUS, Liping NAVARATNE, Primali YAMANO, Michael M CHEN, Ning MANONI, Francesco |
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Snippet | The present disclosure provides compounds useful for the inhibition of KRAS G12D. The compounds have a general Formula I: wherein the variables of Formula I... |
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SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | HETEROCYCLIC COMPOUNDS AND METHODS OF USE |
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