SUBSTITUTED TETRAHYDROFURAN ANALOGS AS MODULATORS OF SODIUM CHANNELS

• Main Authors: SKERRATT, Sarah, CARVALHO MEIRELES, Lidio Marx, SHAW, David Matthew, PONTILLO, Joseph, FRAYSSE, Damien, GALAN, Bhairavi, MUI, James Jun Bon, STAMOS, Dean, CHUDYK, Ewa Iwona, GEDDIS, Stephen Michael, PULLIN, Robert, KNEGTEL, Ronald Marcellus, SCHMIDT, Yvonne, AUSTIN, James Robert, JACQUES, Reece, NORTH, Kiri, ETXEBARRIA JARDI, Gorka, HURLEY, Dennis James, HADIDA RUAH, Sara S, NEUBERT, Timothy Donald, BECK, Elizabeth Mary, STORCK, Pierre-Henri, THOMSON, Stephen Andrew, VIRANI, Anisa Nizarali, AHMAD, Nadia M, KINTZER, Alexander, DURRANT, Steven John, PINDER, Joanne Louise, WRAY, Christopher, SOUSA, Bruno Artur
• Format: Patent
• Language: English
• Published: 30.11.2023
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Compounds of formula I, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable sal...