HUMAN FIBROBLAST GROWTH FACTOR 1 (FGF-1) MUTEINS, THEIR DIMERS AND USES

The present invention relates to human fibroblast growth factor (FGF-1) muteins having decreased mitogenicity, dimers of human FGF-1 muteins, as well as such human FGF-1 muteins and dimers of such muteins for use in reducing blood glucose level, particularly for use in the treatment of diabetes.

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Bibliographic Details
Main Authors ZAKRZEWSKA, Małgorzata Urszula, DRZAZGA, Ewa, BUDA, Paweł, CZYREK, Aleksandra Anna, KROWARSCH, Daniel Rafał, PIECZYKOLAN, Jerzy Szczepan, BAZYDŁO-GUZENDA, Katarzyna, WIECZOREK, Maciej, OTLEWSKI, Jacek Józef, JANISZEWSKI, Michał Mieczysław
Format Patent
LanguageEnglish
Published 21.12.2023
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention relates to human fibroblast growth factor (FGF-1) muteins having decreased mitogenicity, dimers of human FGF-1 muteins, as well as such human FGF-1 muteins and dimers of such muteins for use in reducing blood glucose level, particularly for use in the treatment of diabetes.
Bibliography:Application Number: AU20220279881