Binding proteins recognizing HA-1 antigen and uses thereof

• Main Authors: BOUDOT, Antoine J, NAYAR, Ribhu, MACBEATH, Gavin, BASINSKI, Andrew S, JUREWICZ, Mollie M, JANGALWE, Sonal, XU, Qikai, KULA, Tomasz
• Format: Patent
• Language: English
• Published: 03.11.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

Abstract The specification discloses binding protein(s) comprising a T cell receptor (TCR) alpha chain CDR sequence that recognises HA-1 antigen. Further disclosed are nucleic acids encoding the same and the use of said nucleic acids and vectors comprising them in the production of host cells capabl...