Targeting Degradable Nano-Drug Carrier for Chemo/Photothermal Synergistic Therapy and Preparation Method Thereof
Abstract The present invention discloses a targeting degradable nanometer drug carrier for optic-thermal collaborative chemotherapy and a preparation method thereof The preparation method of the targeting degradable nanometer drug carrier for optic-thermal collaborative chemotherapy comprises: (1) p...
Saved in:
Main Authors | , , , , , , , |
---|---|
Format | Patent |
Language | English |
Published |
13.04.2023
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Abstract The present invention discloses a targeting degradable nanometer drug carrier for optic-thermal collaborative chemotherapy and a preparation method thereof The preparation method of the targeting degradable nanometer drug carrier for optic-thermal collaborative chemotherapy comprises: (1) preparing polydopamine-doped mesoporous silica; (2) conducting amination modification on the polydopamine-doped mesoporous silica; (3) loading an anti-cancer drug; (4) conducting modification by using activated carboxymethyl chitosan and folic acid in sequence; and (5) dispersing a product in the step (4) into a PBS solution, and conducting filtering to obtain the targeting degradable nanometer drug carrier for optic-thermal collaborative chemotherapy. For the targeting degradable nanometer drug carrier for optic-thermal collaborative chemotherapy and the preparation method thereof of the present invention, the drug carrier has high biocompatibility, degradability and targeting characteristic and is an effective way of improving the effect of treating tumors. |
---|---|
AbstractList | Abstract The present invention discloses a targeting degradable nanometer drug carrier for optic-thermal collaborative chemotherapy and a preparation method thereof The preparation method of the targeting degradable nanometer drug carrier for optic-thermal collaborative chemotherapy comprises: (1) preparing polydopamine-doped mesoporous silica; (2) conducting amination modification on the polydopamine-doped mesoporous silica; (3) loading an anti-cancer drug; (4) conducting modification by using activated carboxymethyl chitosan and folic acid in sequence; and (5) dispersing a product in the step (4) into a PBS solution, and conducting filtering to obtain the targeting degradable nanometer drug carrier for optic-thermal collaborative chemotherapy. For the targeting degradable nanometer drug carrier for optic-thermal collaborative chemotherapy and the preparation method thereof of the present invention, the drug carrier has high biocompatibility, degradability and targeting characteristic and is an effective way of improving the effect of treating tumors. |
Author | Liu, Zhiyong Lin, Fuli Li, Wenjuan Yang, Shengchao Cui, Lin Meng, Guihua Wu, Jianning Yang, Yiping |
Author_xml | – fullname: Yang, Yiping – fullname: Lin, Fuli – fullname: Li, Wenjuan – fullname: Cui, Lin – fullname: Meng, Guihua – fullname: Liu, Zhiyong – fullname: Wu, Jianning – fullname: Yang, Shengchao |
BookMark | eNqNirsOgkAQAK_Qwtc_bGFLFCykFdDYaEzEmqyw3F0Ct5flLPh7jfEDrCaZmbmaOHY0U75E0RSs01CQFmzw2RFc0XFUyEtDjiKWBFoWyA31vLkZDhwMSY8d3EdHou0QbA3lx6EfAV0DNyGPgsGygwsFw803E7dLNW2xG2j140KtT8cyP0fkuaLBY02OQnV4JNskSeI43adZFu_-3N4U4kYS |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
ExternalDocumentID | AU2022211878BB1 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_AU2022211878BB13 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 13:05:40 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_AU2022211878BB13 |
Notes | Application Number: AU20220211878 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230413&DB=EPODOC&CC=AU&NR=2022211878B1 |
ParticipantIDs | epo_espacenet_AU2022211878BB1 |
PublicationCentury | 2000 |
PublicationDate | 20230413 |
PublicationDateYYYYMMDD | 2023-04-13 |
PublicationDate_xml | – month: 04 year: 2023 text: 20230413 day: 13 |
PublicationDecade | 2020 |
PublicationYear | 2023 |
RelatedCompanies | SHIHEZI UNIVERSITY |
RelatedCompanies_xml | – name: SHIHEZI UNIVERSITY |
Score | 3.4588847 |
Snippet | Abstract The present invention discloses a targeting degradable nanometer drug carrier for optic-thermal collaborative chemotherapy and a preparation method... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
Title | Targeting Degradable Nano-Drug Carrier for Chemo/Photothermal Synergistic Therapy and Preparation Method Thereof |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230413&DB=EPODOC&locale=&CC=AU&NR=2022211878B1 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV3fS8MwED7GFPVNp-KvSR5G38rWppvtwxDbbgxhW9FO9jbSNlVhtqPrEP9777JN96QvoeTgSA8ud5fk-w6gEXMR81hGepK0Hd2yHanbJschxWWbjmHdccI7D0edwcR6nLanFZhvsTCKJ_RTkSOiR8Xo76Xarxe_h1i-elu5bEbvOJXf98Our22qYzrhNLjmu91eMPbHnuZ5WElqoyeSmSa11rZdrJX2KJEmpv3ei0u4lMVuUOkfw36A-rLyBCoyq8Ght-29VoOD4ebKGz833rc8hUWonm1jsGE-cTwkBHtiuD_mul-sXpknCuo_xzAPZaQsbwZveakgVh9izp6_COeniJlZuCYTYCJLWFDINQF4nrGhaiitxDJPz6DR74XeQMelz34sNXuY7Pyna_BzqGZ5Ji-AOUaEiVEraksztWwhheBWK3ZSYWOFF3WMS6j_qerqH_k1HJH56Z7F4DdQLYuVrGO4LqNbZeVvUZGatQ |
link.rule.ids | 230,309,786,891,25594,76906 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV1LT8JAEJ4QNOJNUeML3QPprYF2C7QHYmwrQaXQaDHcyLbdqgm2pJQY_72zCygnvTSbTjLZR2ZnZne_bwDqEWURjXioxnHLUg3T4qqpU_wk2G3d0owOFXhnb9juj42HSWtSgtkGCyN5Qj8lOSJaVIT2Xsj9ev57iOXKt5WLRviOv7KbXtB1lXV2LE44Naq4dvfOH7kjR3EczCSV4ZOQ6boorW3amCvtdAQ_rwieXmyBS5lvO5XeAez6qC8tDqHE0ypUnE3ttSrseesrb2yurW9xBPNAPttGZ0NcwfEQC9gTwf0xU918-Uoclov6cwTjUCKUZQ3_LSskxOqDzcjzl8D5SWJmEqzIBAhLY-LnfEUAnqXEkwWlpZhnyTHUe3eB01ex69OfmZrejrfGaWv0BMpplvJTIJYWYmDUDFtcTwyTccao0YyshJmY4YVt7Qxqf6o6_0d-DZV-4A2mg_vh4wXsi6UQdy4avYRykS95DV13EV7JGf8Gt8mdog |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Targeting+Degradable+Nano-Drug+Carrier+for+Chemo%2FPhotothermal+Synergistic+Therapy+and+Preparation+Method+Thereof&rft.inventor=Yang%2C+Yiping&rft.inventor=Lin%2C+Fuli&rft.inventor=Li%2C+Wenjuan&rft.inventor=Cui%2C+Lin&rft.inventor=Meng%2C+Guihua&rft.inventor=Liu%2C+Zhiyong&rft.inventor=Wu%2C+Jianning&rft.inventor=Yang%2C+Shengchao&rft.date=2023-04-13&rft.externalDBID=B1&rft.externalDocID=AU2022211878BB1 |