ANALYSIS OF CELLS AND/OR ORGANELLES IN HYDROGEL CAGES

A microfluidic device (10) comprising: - a first wall (12) comprising a first substrate (14) on which a plurality of closed patterns (16) is grafted, - a second wall (18), facing the first wall (12), comprising a second substrate (20), - a plurality of nucleic acids (22) grafted either on the first...

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Main Authors TRAN-AMARELIS, Yvette, CHIRON, Stéphane, GEISLER, Hubert, NGHE, Phillipe, GRIFFITHS, Andrew, MONTI, Fabrice, BLIVET-BAILLY, Gaël, TABELING, Patrick, ABDORAHIM, Marjan
Format Patent
LanguageEnglish
Published 10.08.2023
Subjects
BEER
BIOCHEMISTRY
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
TRANSPORTING
VINEGAR
WINE
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Summary:A microfluidic device (10) comprising: - a first wall (12) comprising a first substrate (14) on which a plurality of closed patterns (16) is grafted, - a second wall (18), facing the first wall (12), comprising a second substrate (20), - a plurality of nucleic acids (22) grafted either on the first substrate (14) or on the second substrate (20), wherein each nucleic acid (22) comprises a barcode that encodes the position of the nucleic acid on said first (14) or second (20) substrate, wherein at least the plurality of closed patterns (16) or the second substrate (20) is made of an actuatable hydrogel which is swellable between a retracted state and a swollen state in which the closed patterns (16) and the second substrate (20) come into contact.
Bibliography:Application Number: AU20220208321