PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF

The present invention provides processes for preparing 5 7H-pyrrolo[2,3-d]pyrimidine derivatives, which are useful as a Janus kinase (JAK) inhibitor, intermediates thereof, and processes for preparing the intermediates. The present invention provides processes for preparing 3-[(3S,4R)-3 methyl-6-(7H...

Full description

Saved in:
Bibliographic Details
Main Authors Takiguchi, Hiromu, Ebdrup, Soren, Watanabe, Takashi, Jensen, Kim Lebek, Vedsoe, Per, Higashi, Akinobu, Takeichi, Tsubasa, Petersen, Anders Klarskov, Inaba, Takashi, Bornholdt, Jan
Format Patent
LanguageEnglish
Published 09.06.2022
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:The present invention provides processes for preparing 5 7H-pyrrolo[2,3-d]pyrimidine derivatives, which are useful as a Janus kinase (JAK) inhibitor, intermediates thereof, and processes for preparing the intermediates. The present invention provides processes for preparing 3-[(3S,4R)-3 methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6 10 diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile using salts of (3S,4R)-1-benzyl-3-methyl-1,6-diazaspiro[3.4]octane with organic acids.
Bibliography:Application Number: AU20220203506