STEM CELL PRIMING COMPOSITION AND PRIMED STEM CELL

The present invention relates to a composition, comprising: TNF-α, IFN-γ, and IFN-α; or TNF-α, IFN-γ, IFN-α, and a vitamin, for promoting immunomodulatory activity and inflammation-modulating ability of stem cells, and a method for preparing stem cells having improved immunomodulatory activity and i...

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Bibliographic Details
Main Authors SONG, Sun Uk, KIM, Si Na
Format Patent
LanguageEnglish
Published 10.08.2023
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention relates to a composition, comprising: TNF-α, IFN-γ, and IFN-α; or TNF-α, IFN-γ, IFN-α, and a vitamin, for promoting immunomodulatory activity and inflammation-modulating ability of stem cells, and a method for preparing stem cells having improved immunomodulatory activity and inflammation-modulating ability by using same. Treatment of stem cells with: TNF-α, IFN-γ, and IFN-α; or TNF-α, IFN-γ, IFN-α, and a vitamin according to the present invention leads to upregulation of the expression of factors associated with the immunoregulatory activity and anti-inflammatory effects of stem cells and thus enables the preparation of functionally reinforced stem cells. The functionally reinforced stem cells thus prepared can find a wide spectrum of applications in various immune, inflammatory disease therapy fields.
Bibliography:Application Number: AU20210410513