Novel quinazoline derivatives as SOS1 inhibitors and use thereof

The present invention relates to a novel quinazoline derivative compound that serves as an SOS1 inhibitor, and a use thereof, and more specifically to: a novel quinazoline derivative compound having inhibitory activity against SOS1 binding to RAS family proteins and/or RAC1; a pharmacologically acce...

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Bibliographic Details
Main Authors KIM, Won Jeoung, KIM, Min Jeong, BAE, In Hwan, KIM, Ji Sook, PARK, Won Gi, CHOI, Jae Yul, AHN, Young Gil
Format Patent
LanguageEnglish
Published 12.09.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a novel quinazoline derivative compound that serves as an SOS1 inhibitor, and a use thereof, and more specifically to: a novel quinazoline derivative compound having inhibitory activity against SOS1 binding to RAS family proteins and/or RAC1; a pharmacologically acceptable salt thereof; or a pharmaceutical composition containing the compound.
Bibliography:Application Number: AU20210409515