Modification of a nanopore forming protein oligomer

Provided herein is a method of chemically modifying a polypeptide or polynucleotide monomer. The monomer may be a monomer of a protein pore such as a monomeric or oligomeric protein pore. Also disclosed are related monomers and oligomers and methods of using the disclosed pores in characterising ana...

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Bibliographic Details
Main Authors MALAVIARACHCHIGE RABEL, Ranga Prabhath, BLACKWELL, Kimberley Emma, KILGOUR, John Joseph, SINGH, Pratik Raj, JAYASINGHE, Lakmal Nishantha, WALLACE, Elizabeth Jayne
Format Patent
LanguageEnglish
Published 13.04.2023
Subjects
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES
MEASURING
METALLURGY
NANOTECHNOLOGY
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICS
SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
TESTING
TRANSPORTING
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Summary:Provided herein is a method of chemically modifying a polypeptide or polynucleotide monomer. The monomer may be a monomer of a protein pore such as a monomeric or oligomeric protein pore. Also disclosed are related monomers and oligomers and methods of using the disclosed pores in characterising analytes.
Bibliography:Application Number: AU20210356235