A NOVEL IL33 FORM, MUTATED FORMS OF IL33, ANTIBODIES, ASSAYS AND METHODS OF USING THE SAME

The present invention provides isolated IL-33 proteins, active fragments thereof and antibodies, antigen binding fragments thereof, against IL-33 proteins. Also provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders.

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Bibliographic Details
Main Authors Butler, Robin, Carmen, Sara, Scott, Ian C, Overed-Sayer, Catherine L, Kemp, Benjamin P, Strain, Martin D, Lowe, David C, Vousden, Katherine A, Sleeman, Matthew, Cohen, Emma S, Rees, David G, Mustelin, Tomas M, England, Elizabeth H, Houslay, Kirsty
Format Patent
LanguageEnglish
Published 17.02.2022
Subjects
AGRICULTURE
ANIMAL HUSBANDRY
CARE OF BIRDS, FISHES, INSECTS
CHEMISTRY
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NEW BREEDS OF ANIMALS
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR
TRAPPING
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Summary:The present invention provides isolated IL-33 proteins, active fragments thereof and antibodies, antigen binding fragments thereof, against IL-33 proteins. Also provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders.
Bibliography:Application Number: AU20210257881