Pegylated Porcine Interferon and Methods of Use Thereof
Disclosed herein are porcine interferon alpha variants (pNF-a) comprising a synthetic amino acid at select locations in 0 pNF-a and a one or two amino acid insertion in the N-terminus after removal of the signal peptide. The pNF-a variants can further be pegylated. Methods of making and administerin...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
30.09.2021
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Subjects | |
Online Access | Get full text |
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Summary: | Disclosed herein are porcine interferon alpha variants (pNF-a) comprising a synthetic amino acid at select locations in 0 pNF-a and a one or two amino acid insertion in the N-terminus after removal of the signal peptide. The pNF-a variants can further be pegylated. Methods of making and administering these compounds to treat virus infections in pigs and formulations comprising the variants are also provided. |
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Bibliography: | Application Number: AU20210229132 |