Cellular uptake

The present invention provides a bile acid or a pharmaceutically acceptable salt thereof, for use in a method of treatment of the human or animal body, which method comprises administering a therapeutic compound to the human or animal body, wherein: a. said bile acid is chenodeoxycholic acid or deox...

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Bibliographic Details
Main Authors NEW, Roger R. C, TRAVERS, Glen
Format Patent
LanguageEnglish
Published 11.08.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a bile acid or a pharmaceutically acceptable salt thereof, for use in a method of treatment of the human or animal body, which method comprises administering a therapeutic compound to the human or animal body, wherein: a. said bile acid is chenodeoxycholic acid or deoxycholic acid, and b. optionally, said bile salt is employed in conjunction with EDTA, c. in said method the bile acid or salt thereof, and EDTA, are used to enable or enhance intracellular uptake of the therapeutic compound.
Bibliography:Application Number: AU20210211236