Fertile transgenic animals useful for producing antibodies bearing human variable regions

The present invention relates inter alia to fertile non-human vertebrates such as mice and rats useful for producing antibodies bearing human variable regions, in which endogenous antibody chain 5 expression has been inactivated. 17779909_1 (GHMatters) P96880.AU.4

Saved in:
Bibliographic Details
Main Authors FRIEDRICH, Glenn A, LEE, E-Chiang
Format Patent
LanguageEnglish
Published 08.07.2021
Subjects
AGRICULTURE
ANIMAL HUSBANDRY
BEER
BIOCHEMISTRY
CARE OF BIRDS, FISHES, INSECTS
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FISHING
FORESTRY
HUMAN NECESSITIES
HUNTING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NEW BREEDS OF ANIMALS
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR
SPIRITS
TRAPPING
VINEGAR
WINE
Online AccessGet full text

Cover

More Information
Summary:The present invention relates inter alia to fertile non-human vertebrates such as mice and rats useful for producing antibodies bearing human variable regions, in which endogenous antibody chain 5 expression has been inactivated. 17779909_1 (GHMatters) P96880.AU.4
Bibliography:Application Number: AU20210203905