Compositions and methods for treating autoimmune diseases and cancers by targeting IGSF8

Methods and compositions are provided. The methods and compositions are used for treating a cancer, and/or an autoimmune disease, by modulating the expression and / or activity of IGSF8 and its binding ligands. The pharmaceutical compositions may include, but are not limited to, antibodies that spec...

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Bibliographic Details
Main Authors XIAO, Tengfei, HU, Xihao, LIU, Xiaole
Format Patent
LanguageEnglish
Published 18.08.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Methods and compositions are provided. The methods and compositions are used for treating a cancer, and/or an autoimmune disease, by modulating the expression and / or activity of IGSF8 and its binding ligands. The pharmaceutical compositions may include, but are not limited to, antibodies that specifically bind human IGSF8, and have an activity of inhibiting IGSF8-mediated immunosuppression in a subject in need thereof.
Bibliography:Application Number: AU20200413633